Journal Article

In press

Erdner, D. L., J. Dyble, L. E. Brand, M. S. Parker, R. C. Stevens, S. K. Moore, K. A. Lefebvre, P. Bienfang, D. M. Anderson, R. R. Bidigare, P. Moeller, M. L. Wrabel, K. A. Hubbard. In press. Centers for Oceans and Human Health: a unified approach to the challenge of harmful algal blooms.

Lefebvre, K. A., A. Robertson. In press. Domoic Acid Exposure Risks: Implications for Human Health. Toxicon.

Lefebvre, K. A., S. C. Tilton, T. K. Bammler, R. P. Beyer, S. Srinouanprachan, P. L. Stapleton, F. M. Farin, E. P. Gallagher. In press. Gene expression profiles in zebrafish brain after acute exposure to domoic acid at symptomatic and aymptomatic doses. Toxicological Sciences.

Moore, S. K., N. Mantua, V. L. Trainer, B. M. Hickey. In press. Long-term measurements of paralytic shellfish toxins in Puget Sound shellfish. Part II: The influence of climate and capacity for prediction. Harmful Algae.

Trainer, V. L., M. L. Wells, W. P. Cochlan, C. G. Trick, K. A. Baugh, B. D. Bill, B. F. Beall, N. Lundholm. In press. A massive bloom of toxigenic Pseudo-nitzschia cuspidata off the Washington State coast. Limnology and Oceanography.

Trainer, V. L. In press. Ecological linkages between physical oceanographic conditions and the seasonal growth and distribution of toxic algal blooms.

Trainer, V. L. In press. Mass Sexual Reproduction In The Toxicgenic Diatoms Pseudo-Nitzschia Australis And P. Pungens (Bacillariophyceae) On The Washington Coast, USA.

2009

Adams, N. G., V. L. Trainer, G. Rocap, R. P. Herwig, L. Hauser. 2009. Genetic population structure of Pseudo-nitzschia pungens (Bacillariophyceae) from the Pacific Northwest and the North Sea. Journal of Phycology, 45:1037-1045.

Casteleyn, G., N. G. Adams, P. Vanormelingen, A. D. Beer, K. Sabbe, W. Vyverman. 2009. Genetic and morphological variation in natural hybrids of the marine diatom Pseudo-nitzschia pungens (Bacillariophycease).

Jester, R., K. A. Baugh, K. A. Lefebvre. 2009. Presence of Alexandrium catenella and paralytic shellfish toxins in finish, shellfish and rock crabs in Monterey Bay, California, USA. Marine Biology.

Moore, S. K., N. Mantua, V. L. Trainer, B. M. Hickey. 2009. Recent trends in paralytic shellfish toxins in Puget Sound, relationships to climate and capacity for prediction of toxic events. Harmful Algae, 8:463-477.

Trainer, V. L., B. M. Hickey, E. J. Lessard, W. P. Cochlan, C. G. Trick, M. L. Wells, J. Herndon, A. MacFadyen, S. Moore. 2009. Variability of Pseudo-nitzschia and domoic acid in the Juan de Fuca Eddy region and its adjacent shelves. Limnology and Oceanography, 54(1).

2008

Anderson, D. M., J. M. Burkholder, W. P. Cochlan, P. M. Glibert, c. J. Gobler, C. Heil, R. Kudela, M. L. Parsons, J. J. Rensel, D. W. Townsend, V. L. Trainer, G. A. Vargo. 2008. Harmful algal blooms and eutrophication: Examples of linkages from selected coastal regions of the United States. Harmful Algae, 8(1):39-53.

Lefebvre, K. A., B. D. Bill, A. Erickson, K. A. Baugh, L. O'Rourke, P. R. Costa, S. L. Nance, V. L. Trainer. 2008. Characterization of dissolved and particulate saxitoxin levels in both field and cultured Alexandrium samples from Sequim Bay, WA. Marine Drugs.

Moore, S. K., V. L. Trainer, N. Mantua, M. S. Parker, E. A. Laws, L. A. Backer, L. E. Fleming. 2008. Centers for Oceans and Human Health: Climate variability, climate change and harmful algal blooms. Environmental Health, 7(S4 doi:10.1186/1476-069X-7-S2-S4).

Moore, S., V. L. Trainer, N. Mantua, M. S. Parker, E. A. Laws, L. C. Backer, L. E. Fleming. 2008. Impacts of climate variability and future climate change on harmful algal blooms and human health. Environmental Health Perspectives, 7(S4 doi:10.1186/1476-069X-7-S2-S4).

Olson, B.M., Lessard, E.J., Cochlan, W.P., and V.L. Trainer. 2008. Intrinsic growth and phytoplankton grazing on toxigenic Pseudo-nitzschia spp. diatoms from the coastal Northeast Pacific. Limnol. Oceanogr. 53(4): 1352-1368.

2007

Lefebvre, K. A., D. P. Noren, I. R. Schultz, S. M. Bogard, B. L. Eberhart. 2007. Uptake, tissue distribution and excretion of domoic acid after oral exposure in coho salmon (Oncorhynchus kisutch). Aquatic Toxicology, 81:266-274.

Stevens, R. C., S. D. Soelberg, B. L. Eberhart, S. Spencer, J. C. Wekell, T. M. Chinowsky, V. L. Trainer, C. E. Furlong. 2007. Detection of the toxin domoic acid from clam extracts using a portable surface plasmon resonance biosensor. Harmful Algae, 6(2).

Trainer, V. L., M. Suddleson. 2007. Monitoring approaches for early warning of domoic acid poisoning events. Oceanography, 18(2):228-237.

Trainer, V. L., W. P. Cochlan, A. Erickson, B. D. Bill, F. Cox, J. A. Borchert, K. A. Lefebvre. 2007. Recent domoic acid closures of shellfish harvest areas in Washington State inland waterways. Harmful Algae.

2006

Adams, N. G., A. MacFadyen, B. M. Hickey, V. L. Trainer. 2006. The nearshore advection of a toxigenic /Pseudo-nitzschia/ bloom and subsequent domoic acid contamination of intertidal bivalves. African Journal of Marine Science.

Bargu, S., K. A. Lefebvre, M. W. Silver. 2006. Effect of dissolved domoic acid on the grazing rate of krill Euphausia pacifica. Marine Ecology Progress Series, 312:169-175.

Baugh, K. A., J. M. Bush, B. D. Bill, K. A. Lefebvre, V. L. Trainer. 2006. Estimates of specific toxicity in several Pseudo-nitzschia species based on culture and field studies. African Journal of Marine Science, 28(2):403-407.

Bill, B. D., F. Cox, R. A. Horner, J. A. Borchert, V. L. Trainer. 2006. The first closure of shellfish harvesting due to domoic acid in Puget Sound, Washington, USA. African Journal of Marine Science, 28(2):435-440.

Marchetti, A., V. L. Trainer, P. Harrison. 2006. Environmental conditions and phytoplankton dynamics associated with Pseudo-nitzchia abundance and domoic acid in the Juan de Fuca eddy. Marine Ecology Progress Series, 281:1-24.

Trainer, V. L., M. Suddleson. 2006. Monitoring approaches for early warning of domoic acid poisoning events in Washington State. Oceanography, 18(2):228-237.

2005

Bricelj, V. M., L. Connell, K. Konoki, S. P. MacQuarrie, T. Scheuer, W. A. Catterall, V. L. Trainer. 2005. Sodium channel mutation leading to saxitoxin resistance in clams increases risk of PSP. Nature, 434:763-767.

Kudela, R., G. Pitcher, F. Figueiras, T. Probyn, T. Moita, V. L. Trainer. 2005. Harmful algal blooms in coastal upwelling systems. Oceanography, 18:184-187.

Lefebvre, K. A., N. Elder, P. K. Hershberger, V. L. Trainer, C. M. Stehr, N. L. Scholz. 2005. Dissolved saxitoxin causes transient inhibition of sensorimotor function in larval Pacific herring (Clupea harengus pallasi). Marine Biology, 147:1393-1402.

Trainer, V. L., M. Suddleson. 2005. Monitoring approaches for early warning of domoic acid events in Washington State. Oceanography, 18:228-237.

Wells, M. L., C. G. Trick, W. P. Cochlan, M. P. Hughes, V. L. Trainer. 2005. Domoic acid: the synergy of iron, copper and the toxicity of diatoms. Limnology and Oceanography, 50:1908-1917.

2004

Lefebvre, K. A., V. L. Trainer, N. L. Scholz. 2004. Morphological abnormalities and sensorimotor deficits in larval fish exposed to dissolved saxitoxin. Aquatic Toxicology, 66(2):159-170.

Marchetti, A., V. L. Trainer, P. Harrison. 2004. Environmental conditions and phytoplankton dynamics associated with Pseudo-nitzschia abundance and domoic acid in the Juan de Fuca eddy. Marine Ecology Progress Series, 281:1-12.

Trainer, V. L., B. D. Bill. 2004. Characterization of a domoic acid binding site from Pacific razor clam. Aquatic Toxicology, 69:125-132.

Wekell, J. C., K. A. Lefebvre, J. Hurst. 2004. The origin of the regulatory limits for PSP and ASP toxins in shellfish. Journal of Shellfish Research, 23:927-930.

2003

Trainer, V. L., B. L. Eberhart, J. C. Wekell, N. G. Adams, L. Hanson, F. Cox, J. Dowell. 2003. Paralytic shellfish toxins in Puget Sound, Washington state. Journal of Shellfish Research, 22:213-223.

2002

Lefebvre, K. A., S. Bargu, T. Kieckhefer, M. W. Silver. 2002. From sanddabs to blue whales: the pervasiveness of domoic acid. Toxicon, 40:971-977.

Scholin, C. A., F. Gulland, G. Doucette, S. Benson, M. Busman, F. P. Chavez, J. Cordaro, R. DeLong, A. DeVogelaere, C. J. Harvey, M. Haulena, K. A. Lefebvre, T. Lipscomb, S. Loscutoff, L. J. Lowenstine, R. Martin III, P. E. Miller, B. McLellan, P. Moeller, C. L. Powell, T. Rowles, P. Silvagni, M. W. Silver, T. Spraker, V. L. Trainer, F. M. Van Dolah. 2002. Mortality of sea lions along the central California coast linked to a toxic diatom bloom. Nature.

Stehr, C. M., L. Connell, K. A. Baugh, B. D. Bill, N. G. Adams, V. L. Trainer. 2002. Morphological, toxicological, and genetic differences among Pseudo-nitzschia (Bacillariophyceae) species in inland embayments and outer coastal waters of Washington State, USA. Journal of Phycology, 38:55-65.

Trainer, V. L., B. M. Hickey, R. A. Horner. 2002. Biological and physical dynamics of domoic acid production off the Washington U.S.A. coast. Limnology and Oceanography, 47:1438-1446.

Trainer, V. L. 2002. Marine biology - Unveiling an ocean phantom. Nature, 418:925-926.

Wekell, J. C., V. L. Trainer, D. Ayres, D. Simons. 2002. A study of spatial variability of domoic acid in razor clams: recommendations for resource management on the Washington coast. Harmful Algae, 1:35-43.

2001

Juhl, A. R., V. L. Trainer, M. I. Latz. 2001. Effect of fluid shear and irradiance on population growth and cellular toxin content of the dinoflagellate Alexandrium fundyense. Limnology and Oceanography, 46(4):758-764.

2000

Adams, N. G., M. Lesoing, V. L. Trainer. 2000. Environmental conditions associated with domoic acid in razor clams on the Washington coast. Journal of Shellfish Research, 19:1007-1015.

Curtis, K. M., V. L. Trainer, S. E. Shumway. 2000. Paralytic shellfish toxins in geoduck clams (Panope abrupta): variability, anatomical distribution, and comparison of two toxin detection methods. Journal of Shellfish Research, 19(1):313-319.

Trainer, V. L., N. G. Adams, B. D. Bill, C. M. Stehr, J. C. Wekell, P. Moeller, M. Busman, D. Woodruff. 2000. Domoic acid production near California upwelling zones, June 1998. Limnology and Oceanography, 45(8):401-440.

1999

Tilbury, K. L., N. G. Adams, C. A. Krone, J. P. Meador, G. Early, U. Varanasi. 1999. Organochlorines in stranded pilot whales (Globicephala melaena) from the Coast of Massachusetts. Archives of Environmental Contamination and Toxicology, 37:125-134.

Trainer, V. L., D. G. Baden. 1999. High-affinity binding of red tide neurotoxins to marine mammal brain. Aquatic Toxicology, 46:139-148.

1998

Collier, T. K., B. F. Anulacion, B. D. Bill. 1998. Hepatic CYP1A in winter flounder (Pleuronectes americanus) along the northeast coast: Results from the National Benthic Surveillance Project. Marine Pollution Bulletin, 37:86-91.

1997

Anulacion, B. F., B. D. Bill, T. K. Collier. 1997. Stability of cytochrome P4501A-associated enzyme activity in cryogenically stored teleost liver samples. Chemosphere, 34:2029-2039.

Lund, J., H. Barnett, C. L. Hatfield, E. J. Gauglitz Jr., J. C. Wekell, B. Rasco. 1997. Domoic acid uptakes and depuration in Dungeness crab (Cancer magister dana 1852). Journal of Shellfish Research, 16(1):225-232.

Meador, J. P., N. G. Adams, E. Casillas, J. L. Bolton. 1997. Comparative bioaccumulation of chlorinated hydrocarbons from sediment by two infaunal invertebrates. Archives of Environmental Contamination and Toxicology, 33:388-400.

1996

Wekell, J. C., R. H. Lorenzana, M. Hogan, H. Barnett. 1996. Survey of paralytic shellfish poison and domoic acid in Puget Sound predatory gastropods. Journal of Shellfish Research, 15(2):231-236.

1995

Hardy, R. W., T. M. Scott, C. L. Hatfield, H. Barnett, E. J. Gauglitz Jr., J. C. Wekell, M. W. Eklund. 1995. Domoic acid in rainbow trout (Oncorhynchus mykiss) feeds. Aquaculture, 131:253-260.

Hatfield, C. L., E. J. Gauglitz Jr., H. Barnett, J. Lund, J. C. Wekell. 1995. The fate of domoic acid in Dungeness crab (Cancer magister) as a function of processing. Journal of Shellfish Research, 14(2):359-363.

Nishimoto, M., B. L. Eberhart, H. R. Sanborn, C. A. Krone, U. Varanasi, J. E. Stein. 1995. Effects of a complex mixture of chemical contaminants of hepatic glutathione, L-cysteine and gamma -glutamylcysteine synthetase in English sole (Pleuronectes vetulus). Environmental Toxicology and Chemistry, 14:461-469.

1994

Hatfield, C. L., J. C. Wekell, E. J. Gauglitz Jr., H. Barnett. 1994. Salt clean-up procedure for the determination of domoic acid by HPLC. Natural Toxins, 2:206-211.

Wekell, J. C., E. J. Gauglitz Jr., H. Barnett, C. L. Hatfield, D. Simons, D. Ayres. 1994. Occurrence of domoic acid in Washington State razor clams (Siliqua patula) during 1991-1993. Natural Toxins, 2:197-205.

Wekell, J. C., E. J. Gauglitz Jr., H. Barnett, C. L. Hatfield, M. W. Eklund. 1994. The occurrence of domoic acid in razor clams (Siliqua patula), dungeness crab (Cancer magister), and anchovies (Engraulismordax). Journal of Shellfish Research, 13:587-593.

1992

Collier, T. K., S. D. Connor, B. L. Eberhart, B. F. Anulacion. 1992. Using Cytochrome P450 to monitor the aquatic environment: Initial results from regional and national surveys. Marine Environmental Research, 34:195-199.

1989

Varanasi, U., W. L. Reichert, B. L. Eberhart, J. E. Stein. 1989. Formation and persistence of benzo(a)pyrene-diolepoxide DNA adducts in liver of English sole (Parophrys vetulus). Chemico-Biological Interactions, 69:203-216.

1986

Varanasi, U., M. Nishimoto, W. L. Reichert, B. L. Eberhart. 1986. Comparative Metabolism of Benzo(a)pyrene and Covalent Binding to Hepatic DNA in English Sole, Starry Flounder, and Rat. Cancer Research, 46:3817-3824.

Wekell, J. C., K. D. Shearer, E. J. Gauglitz Jr. 1986. Zinc supplementation of trout diets: indicators of zinc status. Progressive Fish-Culturist, 48:205-212.

1985

Reichert, W. L., B. L. Eberhart, U. Varanasi. 1985. Exposure of two species of deposit-feeding amphipods to sediment-associated [3H]benzo[a]pyrene: uptake, metabolism and covalent binding to tissue macromolecules. Aquatic Toxicology, 6:45-56.

1983

Wekell, J. C., K. D. Shearer, C. R. Houle. 1983. High zinc supplementation of trout diets. Progressive Fish-Culturist, (3)144-147.

Book

2008

Trainer, V. L., B. M. Hickey, S. S. Bates. 2008. Diatoms.

2007

Bates, S. S., V. L. Trainer. 2007. The Ecology of Harmful Diatoms. Springer Verlag.

2002

Taylor, F. J., V. L. Trainer. (Eds.) 2002. Harmful algal blooms in the PICES region of the North Pacific. PICES Scientific Report no. 23. North Pacific Marine Science Organization, Sidney BC V8L 4B2, iii, 152 p.

Section

2002

Eberhart, B. L., J. C. Wekell, V. L. Trainer, F. Cox, L. Hanson. 2002. PSP in Puget Sound: An historical perspective. In Proceedings of 10th International conference on harmful algae, Oct 21-25, 2002, St. Pete Beach, Florida.

Trainer, V. L. 2002. Harmful algal blooms on the U.S. west coast. Pages 89-118 in Taylor, F. J., V. L. Trainer. (Eds.) Harmful algal blooms in the PICES region of the North Pacific. PICES Scientific Report no. 23.

2001

Trainer, V. L., N. G. Adams, J. C. Wekell. 2001. Domoic acid-producing Pseudo-nitzschia species off the U.S. West Coast associated with toxification events. Pages 46-48 in Hallegraef, G. M. (Ed.) Proceedings of the IX International HAB Conference.

2000

Trainer, V. L., M. A. Poli. 2000. Assays for Dinoflagellate Toxins, Specifically Brevetoxin, Ciguatoxin, and Saxitoxin. pp. 1-19. In Rochat, H., M. Martin-Eauclaire. (Eds.) Animal Toxins. Facts and Protocols.

1999

Wekell, J. C., H. Barnett. 1999. Seafoods: Flavors and Quality. In Wiley, J. (Ed.) Wiley Encyclopedia of Food Science and Technology, Second Edition. Scientific Technical and Medical Publishing, New York, NY.

1993

Nishimoto, M., B. L. Eberhart, H. R. Sanborn, J. E. Stein, U. Varanasi. 1993. Hepatic glutathione in English sole (Pleuronectes vetulus): Response to complex mixtures of xenobiotics. In Proceedings of the 7th PRIMO, Goteborg, Sweden.

Sloan, C. A., N. G. Adams, R. W. Pearce, D. W. Brown, S. Chan. 1993. Northwest Fisheries Science Center Organic Analytical Procedures. Pages 53-97 in Lauenstein, G. G., A. Y. Cantillo. (Eds.) U. S. Dept. Commerce, NOAA Tech. Memo. NOS ORCA 71. Sampling and Analytical Methods of the National Status and Trends Program, National Benthic Surveillance and Mussel Watch Projects 1984-1992. Volume IV. Comprehensive Descriptions of Trace Organic Analytical Methods.

1992

Eberhart, B. L., M. Nishimoto, H. R. Sanborn, J. E. Stein. 1992. Hepatic glutathione levels in flatfish exposed to chemical contaminants. In Proceedings of the 1st annual meeting of the Pacific Northwest Chapter of the Society of Environmental Toxicology and Chemistry, Bellingham, Washington.

1991

Eberhart, B. L., M. Nishimoto, H. R. Sanborn, J. E. Stein, U. Varanasi. 1991. Metabolism of xenobiotics by three species of crustacea. In Proceedings of the 12th annual meeting of the Society of Environmental Toxicology and Chemistry, Nov. 3-7.

1989

Collier, T. K., B. L. Eberhart, J. E. Stein, U. Varanasi. 1989. Aryl hydrocarbon hydroxylase-A. Pages 608-610 in Proceed. Oceans '89.

Stein, J. E., W. L. Reichert, B. L. Eberhart, U. Varanasi. 1989. 32P-Postlabeling of DNA: A sensitive method for assessing environmentally induced genotoxicity. Pages 385-390 in Proceed. Oceans '89.

Report

2005

Pitcher, G., T. Moita, V. L. Trainer, R. Kudela, F. Figueiras, T. Probyn. (Eds.) 2005. Global Ecology and Oceanography of Harmful Algal Blooms - Core research project: HABs in upwelling systems. GEOHAB Report number 3, 88 p.

1997

Casillas, E., B. L. Eberhart, F. Sommers, T. K. Collier, M. M. Krahn, J. E. Stein. 1997. Effects of Chemical Contaminants from the Hylebos Waterway on Growth of Juvenile Chinook Salmon: Hylebos Interpretive Report.

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