NOAA/NMFS/NWFSC TM-36: Fish Injury in the Hylebos Waterway

U.S. Dept Commerce/NOAA/NMFS/NWFSC/Publications

NOAA Tech Memo NMFS NWFSC-36: Fish Injury in the Hylebos Waterway (cont)

TABLE 2.1.
Site of capture and age as risk factors for liver lesions in rock sole, Toxicopathic Injury Study. Logistic regression analyses were used to calculate the odds ratios/relative risks associated with fish age and residence in the Hylebos Waterway. Significant relative risks and p values are shown in bold type. RR_e = estimated relative risk. GM = grand mean; overall odds of lesion occurrence for entire dataset. n= 224 individuals.


LESION	RISK FACTOR	ODDS RATIO/RR_e	P VALUE

Neoplasms	Age	2.43^a	0.016
(GM= 0.6972E-6)	Hylebos Waterway	-------	0.289

Foci of cellular alteration	Age	1.38	0.001
(GM=0.7633E-2)	Hylebos Waterway	-------	0.399

Specific degeneration/	Age	-------	0.939
necrosis	Hylebos Waterway	8.16^b	0.006
(GM=0.1923E-1)

Proliferative lesions	Age	-------	0.928
(GM=0.2752E-1)	Hylebos Waterway	-------	0.127

Hydropic vacuolation	Age	1.28	0.001
GM=0.3327E-1)	Hylebos Waterway	-------	0.951

Any toxicopathic lesion^c	Age	1.21	0.010
(GM=0.2618E-1)	Hylebos Waterway	2.78	0.015

^a Odds ratios for age represent the effect of each additional year of age on the odds of lesion occurrence. In other words, regardless of site of capture, a rock sole in this study is 2.43 times as likely to have a neoplasm with each additional year of age.

^bOdds ratios for site of capture are interpreted relative to the combined age-adjusted lesion occurrence data for rock sole from the reference site at Colvos Passage. Or, a rock sole in the Hylebos Waterway is 8.16 times more likely to have specific degeneration/necrosis than a comparably aged rock sole from the reference site.

^c The "any toxicopathic lesion" category includes fish affected with neoplasms, foci of cellular alteration, specific degeneration/necrosis, or proliferative lesions.

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