U.S. Dept Commerce/NOAA/NMFS/NWFSC/Publications
TABLE 2.3.
Site of capture and age as risk factors for liver lesions in English sole, combined studies.
Logistic regression was used to calculate the odds ratios/estimated relative risks associated
with fish age, and residence in Hylebos Waterway. Significant relative risks and p values are
shown in bold type. RRe = estimated relative risk. GM = grand mean; overall odds of
lesion occurrence for entire dataset. n = 582 individuals.
| LESION | RISK FACTOR | ODDS RATIO/RRe | P VALUE |
| Neoplasms | Age | 1.47a | 0.001 |
| (GM= 0.1903E-2) | Hylebos Waterway | ------- | 0.244 |
| Foci of cellular alteration | Age | 1.41 | 0.001 |
| (GM=0.7399E-2) | Hylebos Waterway | ------- | 0.148 |
| Specific degeneration/ | Age | ------- | 0.572 |
| necrosis | Hylebos Waterway | 25.96b | 0.001 |
| (GM=0.5181E-2) | |||
| Proliferative lesions | Age | ------- | 0.057 |
| (GM=0.2646E-1) | Hylebos Waterway | 4.10 | 0.004 |
| Any toxicopathic lesionc | Age | 1.22 | 0.001 |
| (GM=0.2552E-1) | Hylebos Waterway | 4.37 | 0.001 |
a Odds ratios for age represent the effect of each additional year of age on the odds of disease occurrence. In other words, regardless of site of capture, an English sole in this study is 1.47 times as likely to have a neoplasm with each additional year of age.
b Odds ratios for site of capture are interpreted relative to the age-adjusted lesion occurrence data for all English sole from the reference site at Colvos Passage combined from both studies. In other words, an English sole in the Hylebos Waterway is 25.96 times as likely to have specific degeneration/necrosis than a comparably aged English sole from the reference site.
c The "any toxicopathic lesion" category includes fish affected with neoplasms, foci of cellular alteration, specific degeneration/necrosis, or proliferative lesions.
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