Northwest Fisheries Science Center

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Document Type: Chapter or Section
Center: NWFSC
Document ID: 4424
Type of Book: Technical
Section or Chapter Title: Vaccination against bacterial kidney disease
Book Title: Fish Vaccination
Author: Diane G. Elliott, Gregory D. Wiens, K. Larry Hammell, Linda D. Rhodes
Editor: Roar Gudding, Atle Lillehaug, Øystein Eversen (Eds.)
Publication Year: 2014
Publisher: Wiley-Blackwell
Keywords: bacterial kidney disease,vaccine,infection,salmon,

 Bacterial kidney disease (BKD) of salmonid fishes, caused by Renibacterium salmoninarum, has presented challenges for development of effective vaccines, despite several decades of research. The only vaccine against BKD that is commercially licensed is an injectable preparation containing live cells of Arthrobacter davidanieli (proposed nomenclature), a nonpathogenic environmental bacterium with a relatively close phylogenetic relationship to R. salmoninarum. The stimulatory effect of the live vaccine is believed to be associated with an Arthrobacter surface carbohydrate that is similar to the exopolysaccaride of R. salmoninarum. Significant protection of Atlantic salmon (Salmo salar) against BKD, but limited or no protection of Chinook salmon  (Oncorhynchus tshawytscha) against the disease, has been observed following intraperitoneal injection of the vaccine. Further research is needed for development of more efficacious BKD vaccines for a wider range of salmonid species.

Theme: Recovery, Rebuilding and Sustainability of Marine and Anadromous Species
Foci: Maximize effectiveness and minimize impacts of artificial propagation in recovery, rebuilding and stock sustainability