Northwest Fisheries Science Center

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Document Type: Journal Article
Center: NWFSC
Document ID: 7666
Title: Curing of a plasmid is correlated with an attenuation of virulence in the marine fish pathogen Vibrio anguillarum
Author: Jorge H. Crosa, Linda L. Hodges, Michael H. Schiewe
Publication Year: 1980
Journal: Infection and Immunity
Volume: 27
Issue: 3
Pages: 897-902

 The transposon A sequence Tn1 containing the ampicillin resistance determinants was transposed from RP4 to a plasmid of the marine fish pathogen Vibrio anguillarum.  Curing experiments in which plasmid loss was determined by analysis of the segregation of the ampicillin resistance phenotype showed the association of virulence with the specific V. anguillarum plasmid class.

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Notes: Full text available free from PubMed Central (July 2014)