Northwest Fisheries Science Center

Display All Information

Document Type: Journal Article
Center: OHHI
OHHI ID: OHHI-41
Document ID: 819
Title: Biomarker response and disease susceptibility in juvenile rainbow trout Oncorhynchus mykiss fed a high molecular weight polycyclic aromatic hydrocarbon (PAH) mixture
Author: C. F. Bravo, L. R. Curtis, Mark S. Myers, J. P. Meador, Lyndal L. Johnson, J. Buzitis, T. K. Collier, J. D. Morrow, C. A. Laetz, F. Loge, M. R. Arkoosh
Publication Year: 2011
Journal: Environmental Toxicology and Chemistry
Volume: 30
Issue: 3
Pages: 704-714
DOI: 10.1002/etc.439
Keywords: rainbow trout, PAHs, oxidative stress, AHR, disease susceptibility, Aeromonas salmonicida, toxicity
Abstract:

 Juvenile rainbow trout were fed a diet containing an environmentally relevant mixture of 10 high molecular weight polycyclic aromatic hydrocarbons (PAHs) at a dose of 0.66 or 7.82 µg PAH · g fish−1 · d−1. At 3, 7, 14, and 28 d, biomarkers of aryl hydrocarbon receptor activation (AHR), hepatic microsomal ethoxyresorufin-O-deethylase (EROD) activity, and cytochrome P4501A (CYP1A)-associated staining increased 14- to 26-fold and 6- to 14-fold, respectively, in fish fed 7.82 µg PAH · g fish −1 · d

Northwest Fisheries Science Center

2725 Montlake Boulevard East
Seattle, WA 98112

(206) 860-3200
NWFSC.inquiries@noaa.gov

Get directions to NWFSC facilities

Stay connected:  facebook logo  Twitter logo   YouTube logo  RSS feed logo  Flickr logo

The Northwest Fisheries Science Center (NWFSC) supports the conservation and management of living marine resources and their habitats in the Northeast Pacific Ocean.

Our research assists resource managers in making sound decisions that build sustainable fisheries, recover endangered and threatened species, sustain healthy ecosystems, and reduce risks to human health.