Northwest Fisheries Science Center

Marine Microbes and Toxins Research Activities

Marine Microbes and Toxins Research Topics


Dr. Linda Rhodes
Program Manager
Staff Directory

Zebrafish as a model for V. parahaemolyticus virulence

The ability to monitor increases in pathogenic V. parahaemolyticus populations in shellfish growing areas is crucial for risk assessment models. We have developed a zebrafish (Danio rerio) model to assess differences in virulence of V. parahaemolyticus strains. Zebrafish are easy to handle in a laboratory and have been successfully used to study infections with a number of human bacterial pathogens. The model could be used to differentiate the more pathogenic V. parahaemolyticus strains from those that are less likely to cause infections as well as analyze potential new virulence factors by comparing the strains with mutations in genes of interest with those of the wild-type strains pathogens in Puget Sound and evaluating the potential impacts of climate change.

Project Staff

Rohinee Paranjpye, Mark Myers

Important prior research